Current overview of myasthenia gravis and experience in China

Guo J, Dang D, Li HZ, Li ZY. Current overview of myasthenia gravis and experienc

Jun Guo, Dan Dang, Hong-Zeng Li, Zhu-Yi Li

Department of Neurology, Tangdu Hospital, Fourth M

2014年

127-130

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Myasthenia gravis (MG) is an acquired autoimmune disease affecting synaptic transmission via the neuromuscular junction mainly due to the presence of auto-antibodies targeting acetylcholine receptors. Ocular or generalized MG is clinically diagnosed when the extra-ocular muscles or other muscle groups beyond the extra-ocular muscles are involved. MG occurs in both sexes at any ages from all races but shows a wide variability in incidence and prevalence. Differences in clinical phenotypes of MG patients between West and East countries have been observed. Herein, we review the current concept on epidemiology, classification, and generalized progression in MG, mainly focusing on the differential features from mainland China.。